What is the initial IV/IO bolus dose of amiodarone in pediatric cardiac arrest?

• A. 5 mg/kg
• B. 2 mg/kg
• C. 1 mg/kg
• D. 10 mg/kg

Answer: (A)

Amiodarone is used in pediatric cardiac arrest when the rhythm is shockable (VF/VT) after defibrillation attempts to help prevent recurrences by stabilizing the electrical activity of the heart. The dose is weight-based to fit a child’s size and physiology.

The initial IV/IO bolus is 5 mg/kg. This dose provides a balance between efficacy and safety in children. If the rhythm remains unstable and another bolus is needed, a second 5 mg/kg dose can be given, with a typical total limit of 15 mg/kg (often capped at 450 mg). In practice, amiodarone is preferred over older agents like lidocaine for refractory VF/pVT in kids, due to its overall effectiveness and safety profile.